Dimethylformamide → 3-Methyl-5-(trifluoromethyl)dihydropyrimidine-2,4(1H,3H)-dione

反応式

[CH:1]1([N:2]=[C:3]=[N:4][CH:5]2[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10]2)[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15]1.[O:30]=[CH:31][N:32]([CH3:33])[CH3:34].[OH:16][C:17](=[O:18])[CH:19]([CH2:20][NH:21][C:22](=[O:23])[NH:24][CH3:25])[C:26]([F:27])([F:28])[F:29]>>[O:16]=[C:17]1[CH:19]([C:26]([F:27])([F:28])[F:29])[CH2:20][NH:21][C:22](=[O:23])[N:24]1[CH3:25]

参加物

反応物 3

HCID 6228Dimethylformamide

HCID 10868Dicyclohexylcarbodiimide

HCID 133137911-(2-Hydroxycarbonyl-3,3,3-trifluoropropyl)-3-methylurea

生成物 1

HCID 130049793-Methyl-5-(trifluoromethyl)dihydropyrimidine-2,4(1H,3H)-dione

出典と根拠

ORDレコード: ord-32e6517b690f4c5caa07f95fe92b970c
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…