Hydrochloric Acid → 1-(2-chlorobenzo[d]thiazol-6-yl)-N-ethyl-1-(1H-imidazol-1-yl)-N-methylbutan-2-amine

HRID 1894756ノート

反応式

HRID 1894756 の反応式
Br[C:2]1[S:3][C:4]2[CH:10]=[C:9]([CH:11]([N:19]3[CH:23]=[CH:22][N:21]=[CH:20]3)[CH:12]([N:15]([CH2:17][CH3:18])[CH3:16])[CH2:13][CH3:14])[CH:8]=[CH:7][C:5]=2[N:6]=1.[ClH:24]>>[Cl:24][C:2]1[S:3][C:4]2[CH:10]=[C:9]([CH:11]([N:19]3[CH:23]=[CH:22][N:21]=[CH:20]3)[CH:12]([N:15]([CH2:17][CH3:18])[CH3:16])[CH2:13][CH3:14])[CH:8]=[CH:7][C:5]=2[N:6]=1

参加物

3

反応物 2

HCID 313Hydrochloric AcidHCID 547620861-(2-bromobenzo[d]thiazol-6-yl)-N-ethyl-1-(1H-imidazol-1-yl)-N-methylbutan-2-amine

生成物 1

HCID 547620881-(2-chlorobenzo[d]thiazol-6-yl)-N-ethyl-1-(1H-imidazol-1-yl)-N-methylbutan-2-amine

実験手順

A mixture of 1-(2-bromobenzo[d]thiazol-6-yl)-N-ethyl-1-(1H-imidazol-1-yl)-N-methylbutan-2-amine (5 mg, 0.1 mmol) and 2N HCl (5 mL) was stirred at Rt for 1 h. The mixture was filtered and evaporated to afford 1-(2-chlorobenzo[d]thiazol-6-yl)-N-ethyl-1-(1H-imidazol-1-yl)-N-methylbutan-2-amine. MS ESI: m/z 349.2 [M+H+].

後処理

  1. filtrationThe mixture was filtered
  2. customevaporated

出典と根拠

ORDレコード
ord-321f87fc43c64e03af8acdbfe54409b1
出典データセット
uspto-grants-2013_08
特許番号
US08513291B2

反応ノート

読み込み中…