2-Methyl-6-(3-piperidin-4-ylideneprop-1-ynyl)pyridine → 2-(Piperidin-4-yl)but-3-yn-2-ol
反応式
CC1C=CC=C(C#CC=C2CCNCC2)N=1.[OH:17][C:18]([CH:22]1[CH2:27][CH2:26][N:25](C(OC(C)(C)C)=O)[CH2:24][CH2:23]1)([CH3:21])[C:19]#[CH:20]>>[NH:25]1[CH2:26][CH2:27][CH:22]([C:18]([OH:17])([C:19]#[CH:20])[CH3:21])[CH2:23][CH2:24]1参加物
3
実験手順
The title compounds were obtained following the procedure described for the compound of Example 3 and replacing the Compound of Example 2 with Compound 312a refluxing for 6 h. The crude was used without further purification in the next step.
後処理
- temperaturerefluxing for 6 h
- customThe crude was used without further purification in the next step
出典と根拠
- ORDレコード
- ord-4027678fd64049a5810448a3d002f954
- 出典データセット
- uspto-grants-2013_08
- 特許番号
- US08518916B2
反応ノート
読み込み中…