Phosphorus pentachloride → 2-Chloro-5-nitrobenzo[d]oxazole
反応式
[N+:1]([C:4]1[CH:5]=[CH:6][C:7]2[O:11][C:10](=S)[NH:9][C:8]=2[CH:13]=1)([O-:3])=[O:2].P(Cl)(Cl)(Cl)(Cl)[Cl:15]>P(Cl)(Cl)(Cl)=O>[Cl:15][C:10]1[O:11][C:7]2[CH:6]=[CH:5][C:4]([N+:1]([O-:3])=[O:2])=[CH:13][C:8]=2[N:9]=1参加物
4
反応条件
- 温度
- 100 °C
実験手順
To a solution of 5-nitrobenzo[d]oxazole-2(3H)-thione (2.52 g, 12.86 mmol) in phosphorous oxychloride (21 mL) was added phosphorous pentachloride (2.68 g, 12.86 mmol) in one portion. The mixture was then heated to 100° C. for 2.5 h. After cooling, the excess of phosphorous oxychloride was removed in vacuo and the resulting mixture was used crude without characterisation.
後処理
- temperatureAfter cooling
- customthe excess of phosphorous oxychloride was removed in vacuo
出典と根拠
- ORDレコード
- ord-2a6c58f898884fdba67f882f2f956f54
- 出典データセット
- uspto-grants-2013_08
- 特許番号
- US08518980B2
反応ノート
読み込み中…