Thionyl Chloride → 6-Fluoro-2-naphthoyl chloride

関与物質

反応手順

6-fluoro-2-naphthoic acid (2 g, 10.52 mmol) was stirred in thionyl chloride (21.03 ml) at 80° C. for 4 h in pressure vessel. The mixture was cooled and concentrated. The acid chloride was dried and used as is for next step.

情報源と証拠