Hydrogen iodide → HCID 178506554、化合物

反応式

Cl[C:2]1[CH:7]=[CH:6][N:5]=[C:4]2[NH:8][CH:9]=[N:10][C:3]=12.[IH:11]>>[I:11][C:2]1[CH:7]=[CH:6][N:5]=[C:4]2[NH:8][CH:9]=[N:10][C:3]=12

参加物

反応物 2

HCID 24841Hydrogen iodide

HCID 178478247HCID 178478247、化合物

生成物 1

HCID 178506554HCID 178506554、化合物

実験手順

A mixture of 7-chloro-3H-imidazo[4,5-b]pyridine (1.47 g, 9.64 mmol) and 15 mL of 57% hydriodic acid were reacted at 80° C. for 4 h. After the solid was filtered off it was resubmitted to the reaction with 10 mL of fresh 57% hydriodic acid. The reaction yielded 1.3 g of the product as a black powder, 90% pure.

後処理

customwere reacted at 80° C. for 4 h
filtrationAfter the solid was filtered off it
customwas resubmitted to the reaction with 10 mL of fresh 57% hydriodic acid

出典と根拠

ORDレコード: ord-aa8a22b4106347ec917b9abc2089866a
出典データセット: uspto-grants-2013_08
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08519135B2

反応ノート

読み込み中…

参加物