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1-Ethyl-1H-pyrazole-4-boronic acid, pinacol ester → HCID 53386417、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-Ethyl-1H-pyrazole-4-boronic acid, pinacol ester | HCID 11379045 | — |
| 反応物 | (R)-2-amino-3,3-dimethyl-1-(pyrrolidin-1-yl)butan-1-one hydrochloride | HCID 57516598 | — |
| 反応物 | 1-((R)-2-amino-3,3-dimethyl-butyryl)-piperidine-4-carbonitrile trifluoroacetate | HCID 67386048 | — |
| 反応物 | 4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(2,2,2-trifluoroethyl)-1H-pyrazole | HCID 68923586 | — |
| 生成物 | HCID 53386417 | HCID 53386417 | — |
反応手順
Prepared according to the procedure outlined in Example 2 substituting 1-((R)-2-amino-3,3-dimethyl-butyryl)-piperidine-4-carbonitrile trifluoroacetate for (R)-2-amino-3,3-dimethyl-1-pyrrolidin-1-yl-butan-1-one hydrochloride in Step 1 and 1-(2,2,2-trifluoroethyl)-1H-pyrazole-4-boronic acid pinacol ester for 1-ethyl-1H-pyrazole-4-boronic acid pinacol ester in Step 2. MS: (M+H)+=517.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08518945B2 |
| 出典データセット | uspto-grants-2013_08 |
| ORD ID | ord-5a9d1064aa9e42dc887eddc9e889f345 |
| 出典メモ | uspto-grants-2013_08 |