化工社化工社 化学情報印刷レポート · 研究参考用
Sulfisoxazole → 1-Cyclohexyl-3-[4-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]phenyl]urea
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Sulfisoxazole | HCID 5344 | — |
| 反応物 | Cyclohexyl isocyanate | HCID 18502 | — |
| 生成物 | 1-Cyclohexyl-3-[4-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]phenyl]urea | HCID 4054520 | — |
反応手順
This compound was prepared from 4-amino-N-(3,4-dimethyl-5-isoxazolyl)benzene-sulfonamide and cyclohexyl isocyanate according to the method in Example 110 in 75% crude yield. Further purification was achieved by preparative HPLC (76% recovery), furnishing the pure product as a white solid, m.p. 190°-195° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05571821 |
| 出典データセット | uspto-grants-1996_11 |
| ORD ID | ord-038f879dac3c45869fa859d2befa14a5 |
| 出典メモ | uspto-grants-1996_11 |