3,5-Difluorobiphenyl → 3-Fluoro-5-(4-fluorophenyl)thiophenol

反応式

C[Si](C)(C)CC[S:5][C:6]1[CH:11]=[C:10]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[CH:9]=[C:8]([F:18])[CH:7]=1.[F:21]C1C=C(C2C=CC=CC=2)C=C(F)C=1>>[F:18][C:8]1[CH:7]=[C:6]([SH:5])[CH:11]=[C:10]([C:12]2[CH:17]=[CH:16][C:15]([F:21])=[CH:14][CH:13]=2)[CH:9]=1

参加物

反応物 2

HCID 130223913,5-Difluorobiphenyl

HCID 57070644S-(2-Trimethylsilylethyl)-3-fluoro-5-phenylthiophenol

生成物 1

HCID 233702153-Fluoro-5-(4-fluorophenyl)thiophenol

実験手順

Following the procedure described in Thiophenol 1, Step 3, but substituting S-(2-trimethylsilylethyl)-3-fluoro-5-(4-fluorophenyl)thiophenol for S-(2-trimethylsilylethyl)-3-fluoro-5-phenylthiophenol, the title compound was obtained as a liquid.

出典と根拠

ORDレコード: ord-7f85c77d0e3a4ff6b65899aff9f48c70
出典データセット: uspto-grants-1996_11
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US05576338

反応ノート

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