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2-Nitrobenzyl chloride → 2-[(2-Nitrophenyl)methyl]isoindole-1,3-dione
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Nitrobenzyl chloride | HCID 11921 | — |
| 反応物 | Potassium phthalimide | HCID 3356745 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | 2-[(2-Nitrophenyl)methyl]isoindole-1,3-dione | HCID 319537 | — |
反応手順
The mixture of 54.0 of N-potassium phthalimide, 50.0 g of o-nitrobenzyl chloride and 120 ml of dimethylformamide is refluxed for 3 hours and poured into 900 ml of ice-water while stirring. After 30 minutes, it is filtered, and the residue washed with water, to yield the N-o-nitrobenzyl-phthalimide melting at 190°-209°.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04362666 |
| 出典データセット | uspto-grants-1982_12 |
| ORD ID | ord-eead5c0713aa4ff4979b78921b536494 |
| 出典メモ | uspto-grants-1982_12 |