Ammonia → HCID 178512201、化合物

HRID 1902329

反応式

HRID 1902329 の反応式
[OH:1][CH2:2][C:3]1[CH:4]=[C:5]([NH:9][C:10]([NH:12][CH2:13][C:14]([F:17])([F:16])[F:15])=S)[CH:6]=[CH:7][CH:8]=1.[NH3:18]>>[OH:1][CH2:2][C:3]1[CH:4]=[C:5]([NH:9][C:10]([NH:12][CH2:13][C:14]([F:17])([F:16])[F:15])=[NH:18])[CH:6]=[CH:7][CH:8]=1

参加物

3

反応物 2

HCID 222AmmoniaHCID 212987211-(3-Hydroxymethylphenyl)-3-(2,2,2-trifluoroethyl)thiourea

生成物 1

HCID 178512201HCID 178512201、化合物

実験手順

The above thiourea (1.32 g.) was stirred in 1.6 N alcoholic ammonia (50 ml.) with mercuric oxide (3.4 g.) for 17 hours at 20°. The resulting mixture was clarified on the centrifuge and the suspernatant was evaporated in vacuo to a syrup which was further dried at 70°/0.1 m.m. to give 1-(3-hydroxymethylphenyl)-3-(2,2,2-trifluoroethyl)guanidine. The n.m.r. spectrum in d6 dimethylsulphoxide using tetramethyl silane as internal standard (δ=0) had the following resonances (δ):-6.9 (4H, multiplet); 4.4 (2H, singlet); 3.9 (2H, quartet).

後処理

  1. customthe suspernatant was evaporated in vacuo to a syrup which
  2. customwas further dried at 70°/0.1 m

出典と根拠

ORDレコード
ord-7e32757a7db948a89995ce6010a5ba7a
出典データセット
uspto-grants-1982_12
特許番号
US04362728

関連ノート

読み込み中…