Hydrochloric Acid → 4-Oxo-5-phenyl-4H-pyran-2-carboxylic acid

反応式

[O:1]=[C:2]1[C:7]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)=[CH:6][O:5][C:4]([C:14]([O:16]CC)=[O:15])=[CH:3]1.Cl>>[O:1]=[C:2]1[C:7]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)=[CH:6][O:5][C:4]([C:14]([OH:16])=[O:15])=[CH:3]1

参加物

反応物 2

HCID 313Hydrochloric Acid

HCID 13091198Ethyl 4-oxo-5-phenyl-4H-pyran-2-carboxylate

生成物 1

HCID 130911614-Oxo-5-phenyl-4H-pyran-2-carboxylic acid

実験手順

Ethyl 4-oxo-5-phenyl-4H-pyran-2-carboxylate (4.9 g) was heated with concentrated hydrochloric acid (12 ml) on a steam bath for 11/2 hours. The mixture was cooled and the solid title product was recrystallised from ethyl acetate-dimethylformamide (mp 225°-227° C. with decomposition).

後処理

temperatureThe mixture was cooled
customthe solid title product was recrystallised from ethyl acetate-dimethylformamide (mp 225°-227° C. with decomposition)

出典と根拠

ORDレコード: ord-36ff2856ffc34546ab9ae5748c545023
出典データセット: uspto-grants-1982_12
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04364956

反応ノート

読み込み中…

参加物