Ammonia → 4-oxo-5-phenyl-4H-pyran-2-carboxamide
反応式
[NH3:1].[O:2]=[C:3]1[C:8]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)=[CH:7][O:6][C:5]([C:15]([O:17]CC)=O)=[CH:4]1>C(O)C>[O:2]=[C:3]1[C:8]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)=[CH:7][O:6][C:5]([C:15]([NH2:1])=[O:17])=[CH:4]1参加物
4
実験手順
Concentrated ammonia solution (40 ml) was added to a stirred suspension of ethyl 4-oxo-5-phenyl-4H-pyran-2-carboxylate (4.8 g) in ethanol (40 ml) at 10°-15° C. The mixture was then stirred for 30 minutes at 10°-15° C. Then the solid product was recrystallised from dimethylformamide-ethanol to give 4-oxo-5-phenyl-4H-pyran-2-carboxamide (mp 245°-248° with decomposition).
後処理
- customThen the solid product was recrystallised from dimethylformamide-ethanol
出典と根拠
- ORDレコード
- ord-8aea5cde7832434b99fa700cf908ebf1
- 出典データセット
- uspto-grants-1982_12
- 特許番号
- US04364956
反応ノート
読み込み中…