HCID 13273322、化合物 → 2-(Difluoromethyl)hex-5-enoic acid
反応式
[C:1]([C:4]([CH:12]([F:14])[F:13])([CH2:8][CH2:9][CH:10]=[CH2:11])C(O)=O)([OH:3])=[O:2]>C(O)(=O)C>[F:13][CH:12]([F:14])[CH:4]([CH2:8][CH2:9][CH:10]=[CH2:11])[C:1]([OH:3])=[O:2]参加物
3
反応条件
- 温度
- 110 °C
実験手順
2-Carboxy 2-difluoromethyl 5-hexenoic acid, prepared as in Step C (1.040 g, 5 mM) is dissolved in glacial acetic acid (5 ml) and the mixture is heated at 110° C. for 16 hours. The solvent is evaporated in vacuo yielding a colorless oil. The acid is isolated by distillation under reduced pressure. 0.585 g (yield 71%). Bp: 67° C./0.01 mm Hg.
後処理
- customThe solvent is evaporated in vacuo
- customyielding a colorless oil
- customThe acid is isolated by distillation under reduced pressure
出典と根拠
- ORDレコード
- ord-a910656b234743efa0dc2c514ab18484
- 出典データセット
- uspto-grants-1984_03
- 特許番号
- US04435425
反応ノート
読み込み中…