Bromine → HCID 13268202、化合物

HRID 1903380ノート

反応式

HRID 1903380 の反応式
[CH3:1][C:2]([CH2:8][CH3:9])([CH2:6][CH3:7])[C:3](=[O:5])[CH3:4].[Br:10]Br.[Cl-].[Al+3].[Cl-].[Cl-]>C(OCC)C>[Br:10][CH2:4][C:3](=[O:5])[C:2]([CH3:1])([CH2:8][CH3:9])[CH2:6][CH3:7]

参加物

5

反応物 3

HCID 24408BromineHCID 1405902-Pentanone, 3-ethyl-3-methyl-HCID 6451240Aluminum(III) Chloride

生成物 1

HCID 13268202HCID 13268202、化合物

試薬・触媒・溶媒 1

HCID 3283Diethyl Ether溶媒

実験手順

To a solution of 9.0 g of 3-methyl-3-ethyl-2-pentanone in 100 ml diethyl ether cooled to about 0°-5° C. with an ice bath was added 3.6 ml bromine. The reaction mixture was allowed to warm to room temperature and a catalytic amount of aluminum chloride was added. The mixture was stirred for 30 minutes and washed with water and a saturated sodium bicarbonate solution. The organic phase was separated, dried over anhydrous sodium sulfate and evaporated under vacuum to provide an oil. The oil was distilled under vacuum to provide 6.3 g of product. bp=100°-114° C. at 16 mm.

後処理

  1. washwashed with water
  2. customThe organic phase was separated
  3. dry with materialdried over anhydrous sodium sulfate
  4. customevaporated under vacuum
  5. customto provide an oil
  6. distillationThe oil was distilled under vacuum

出典と根拠

ORDレコード
ord-45f38bed5bd047d0ab1e4bec698e7d67
出典データセット
uspto-grants-1984_03
特許番号
US04436549

反応ノート

読み込み中…