Sodium disulfide → 3-(3-Phenyl-1-propenyl)aniline

HRID 1903651

反応式

HRID 1903651 の反応式
[C:1]1([CH2:7][CH:8]=[CH:9][C:10]2[CH:11]=[C:12]([N+:16]([O-])=O)[CH:13]=[CH:14][CH:15]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.O.N.[S-][S-].[Na+].[Na+]>C(O)C>[C:1]1([CH2:7][CH:8]=[CH:9][C:10]2[CH:11]=[C:12]([CH:13]=[CH:14][CH:15]=2)[NH2:16])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

参加物

5

反応物 3

HCID 89870Sodium disulfideHCID 12896473Azane;hydrateHCID 538829723-(3-Phenyl-1-propenyl)nitrobenzene

生成物 1

HCID 540429893-(3-Phenyl-1-propenyl)aniline収率 85%

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

To a solution of 3-(3-phenyl-1-propenyl)nitrobenzene (10.5 g) in 200 ml of ethanol were added 70 ml of 35% ammonia water and 44 g of sodium disulfide. After heating under reflux for 2 hours, the solvent was removed under reduced pressure, followed by extraction with ethyl acetate. The extract was washed with water and dried over magnesium sulfate. The solvent was removed by distillation under reduced pressure to give 7.8 g of 3-(3-phenyl-1-propenyl)aniline (yield, 85%). B.P. 128°-130° C./0.09 mmHg.

後処理

  1. temperatureAfter heating
  2. temperatureunder reflux for 2 hours
  3. customthe solvent was removed under reduced pressure
  4. extractionfollowed by extraction with ethyl acetate
  5. washThe extract was washed with water
  6. dry with materialdried over magnesium sulfate
  7. customThe solvent was removed by distillation under reduced pressure

出典と根拠

ORDレコード
ord-0fca6851e60a46b480237d921ebc77b7
出典データセット
uspto-grants-1984_03
特許番号
US04437880

関連ノート

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