1,1'-Biphenyl, mixt. with 1,1'-oxybis(benzene) → HCID 20038764、化合物

反応式

[C:1]([C:4](=[CH:10][NH:11][C:12]1[CH:13]=[N:14][NH:15][CH:16]=1)[C:5]([O:7]CC)=O)(=[O:3])[CH3:2].C1C=CC(C2C=CC=CC=2)=CC=1.C1C=CC(OC2C=CC=CC=2)=CC=1>>[C:1]([C:4]1[C:5](=[O:7])[C:13]2[NH:14][N:15]=[CH:16][C:12]=2[NH:11][CH:10]=1)(=[O:3])[CH3:2]

参加物

反応物 2

HCID 246701,1'-Biphenyl, mixt. with 1,1'-oxybis(benzene)

HCID 178471961HCID 178471961、化合物

生成物 1

HCID 20038764HCID 20038764、化合物収率 74%

実験手順

Ethyl 2-acetyl-3-(4-pyrazolylamino)acrylate (D13, 1.0 g, 4.5 mmol) was added to boiling Dowtherm A, and the solution was heated under reflux for 20 min. The mixture was allowed to cool and 60°-80° petroleum ether (100 ml) was added. The solid was filtered off and washed well with petroleum ether to give the title compound (590 mg, 74%), m.p.>320° C.

後処理

temperaturethe solution was heated
temperatureunder reflux for 20 min
additionwas added
filtrationThe solid was filtered off
washwashed well with petroleum ether

出典と根拠

ORDレコード: ord-68b55c522cd24ab4a8706d8573fb52e2
出典データセット: uspto-grants-1989_06
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04837238

反応ノート

読み込み中…

参加物