Chloroacetic Acid → 2-(2,4-Difluorophenyl)ethoxyacetic acid
反応式
[F:1][C:2]1[CH:10]=[C:9]([F:11])[CH:8]=[CH:7][C:3]=1[CH2:4][CH2:5][OH:6].Cl[CH2:13][C:14]([OH:16])=[O:15]>>[F:1][C:2]1[CH:10]=[C:9]([F:11])[CH:8]=[CH:7][C:3]=1[CH2:4][CH2:5][O:6][CH2:13][C:14]([OH:16])=[O:15]参加物
3
反応条件
- 温度
- 120 °C
実験手順
3.63 g of 2,4-difluorophenethyl alcohol were reacted with 2.17 g of chloroacetic acid in a manner analogous to that described in Example 1(a), except that the reaction mixture was heated at 120° C. for 1 hour, to give 2.7 g (54%) of 2-(2,4-difluorophenyl)ethoxyacetic acid in the form of an oil which was homogeneous according to chromatography.
出典と根拠
- ORDレコード
- ord-1af4a45575fc4ec6904e5fe919aa2779
- 出典データセット
- uspto-grants-1987_03
- 特許番号
- US04649160
反応ノート
読み込み中…