化工社化工社 化学情報印刷レポート · 研究参考用
Selenium Dioxide → 4-Benzyloxy-3-hydroxymethylphenylglyoxal
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Selenium Dioxide | HCID 24007 | — |
| 反応物 | 1-[3-(Hydroxymethyl)-4-(phenylmethoxy)phenyl]ethanone | HCID 12969323 | — |
| 溶媒 | Water | HCID 962 | — |
| 溶媒 | 1,4-Dioxane | HCID 31275 | — |
| 生成物 | 4-Benzyloxy-3-hydroxymethylphenylglyoxal | HCID 20134166 | — |
反応手順
1-(4-Benzyloxy-3-hydroxymethylphenyl)ethanone (10.4 g) was added portionwise to a stirred solution of selenium dioxide (5.5 g) in water (0.9 ml) and dioxan (100 ml) at 60 °. The mixture was stirred under reflux for 4 hours, filtered whilst hot and allowed to cool. The solid was collected and recrystallised from dioxan as a dimer, mp 180°-181° (7.7 g). (d6DMSO) 5.13 (1H, s), 4.94 (1H, s), 4.72 (2H, s), 3.42 (1H, d, J=10 Hz), 3.24 (1H, d, J=10 Hz), 2.72 (1H, m), 2.54 (5H, m), 2.04 (1H, m), 1.46 (1H, m).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04654371 |
| 出典データセット | uspto-grants-1987_03 |
| ORD ID | ord-f9147e95a14c4abfa2bab9bcfe1bd4f4 |
| 出典メモ | uspto-grants-1987_03 |