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tert-Butyl hydroperoxide → (trans)-3-(7-Phenyl-1,2-heptadiene-4,6-diynyl)oxiranemethanol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | tert-Butyl hydroperoxide | HCID 6410 | — |
| 反応物 | 10-Phenyl-7,9-decadiyne-2,4,5-trien-1-ol | HCID 53943077 | — |
| 触媒 | Bis(2,4-pentanedionato)vanadium(IV) Oxide | HCID 16217092 | — |
| 溶媒 | Benzene | HCID 241 | — |
| 生成物 | (trans)-3-(7-Phenyl-1,2-heptadiene-4,6-diynyl)oxiranemethanol | HCID 86740795 | — |
反応手順
To a stirred solution of 20 mg (0.090 mmole) of 10-phenyl-7,9-decadiyne-2,4,5-trien-1-ol in 4 ml of benzene was added 2 mg of vanadyl acetylacetonate and 50 μl (0.26 mmole) of a 5.43M solution of t-butyl hydroperoxide in benzene. The mixture was stirred for two hours. The mixture was concentrated and the residue was purified via flash chromatography to afford 7 mg of the title compound as an approximately 1:1 mixture of diastereomers.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04654426 |
| 出典データセット | uspto-grants-1987_03 |
| ORD ID | ord-fa7e7b7cf5b94c54b0702566d67516c3 |
| 出典メモ | uspto-grants-1987_03 |