5-(2-Dimethylamino-ethoxy)-2-nitro-phenylamine → 4-(2-(Dimethylamino)ethoxy)benzene-1,2-diamine

HRID 1909009ノート

反応式

HRID 1909009 の反応式
[CH3:1][N:2]([CH3:16])[CH2:3][CH2:4][O:5][C:6]1[CH:7]=[CH:8][C:9]([N+:13]([O-])=O)=[C:10]([NH2:12])[CH:11]=1>CCO>[CH3:1][N:2]([CH3:16])[CH2:3][CH2:4][O:5][C:6]1[CH:11]=[C:10]([NH2:12])[C:9]([NH2:13])=[CH:8][CH:7]=1

参加物

3

反応物 1

HCID 203767455-(2-Dimethylamino-ethoxy)-2-nitro-phenylamine

生成物 1

HCID 221677014-(2-(Dimethylamino)ethoxy)benzene-1,2-diamine収率 90.3%

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

5-(2-Dimethylamino-ethoxy)-2-nitro-phenylamine (0.85 g, 3.77 mmol) was dissolved in EtOH and shaken under an atmosphere of H2 for 6 hours. The catalyst was removed by filtration. Evaporation in vacuo gave 4-(2-Dimethylamino-ethoxy)-benzene-1,2-diamine as a dark yellow oil (0.665 g, 90%). MS(ESI) m/z 196.0 (M+H)+

後処理

  1. customThe catalyst was removed by filtration
  2. customEvaporation in vacuo

出典と根拠

ORDレコード
ord-dbe3ed15eff0481487933aa4d5ab9292
出典データセット
uspto-grants-2013_12
特許番号
US08598217B2

反応ノート

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