Toluene → 4-[4-(Trifluoromethoxy)phenoxy]-1-{4-[(2,2,4-trimethyl-1,3-dioxolan-4-yl)methoxy]phenyl}piperidine

反応式

Br[C:2]1[CH:17]=[CH:16][C:5]([O:6][CH2:7][C:8]2([CH3:15])[CH2:12][O:11][C:10]([CH3:14])([CH3:13])[O:9]2)=[CH:4][CH:3]=1.[F:18][C:19]([F:35])([F:34])[O:20][C:21]1[CH:33]=[CH:32][C:24]([O:25][CH:26]2[CH2:31][CH2:30][NH:29][CH2:28][CH2:27]2)=[CH:23][CH:22]=1.CC(C)([O-])C.[Na+].C1(C)C=CC=CC=1>C([O-])(=O)C.[Pd+2].C([O-])(=O)C.C1([B-](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.C(P(C(C)(C)C)C(C)(C)C)(C)(C)C.O.C(OCC)(=O)C>[F:35][C:19]([F:18])([F:34])[O:20][C:21]1[CH:33]=[CH:32][C:24]([O:25][CH:26]2[CH2:27][CH2:28][N:29]([C:2]3[CH:17]=[CH:16][C:5]([O:6][CH2:7][C:8]4([CH3:15])[CH2:12][O:11][C:10]([CH3:14])([CH3:13])[O:9]4)=[CH:4][CH:3]=3)[CH2:30][CH2:31]2)=[CH:23][CH:22]=1