化工社化工社 化学情報印刷レポート · 研究参考用
methyl 2-amino-1H-benzo[d]imidazole-4-carboxylate → 2-amino-6-pyridin-4-yl-1H-benzoimidazole-4-carboxylic acid methyl ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | methyl 2-amino-1H-benzo[d]imidazole-4-carboxylate | HCID 24730367 | — |
| 反応物 | 2-Amino-3-nitro-5-pyridin-4-yl-benzoic acid methyl ester | HCID 66940533 | — |
| 生成物 | 2-amino-6-pyridin-4-yl-1H-benzoimidazole-4-carboxylic acid methyl ester | HCID 66940503 | 50% |
反応手順
0.25 g (50% overall yield) of 2-amino-6-pyridin-4-yl-1H-benzoimidazole-4-carboxylic acid methyl ester was synthesized according to procedures described for the synthesis of 2-Amino-1H-benzoimidazole-4-carboxylic acid methyl ester (intermediate A) starting from 0.5 g (1.8 mmol) of above synthesized 2-Amino-3-nitro-5-pyridin-4-yl-benzoic acid methyl ester. LCMS: 269 (M+1)+.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08598353B2 |
| 出典データセット | uspto-grants-2013_12 |
| ORD ID | ord-897508facca94758b487c46a4f770df0 |
| 出典メモ | uspto-grants-2013_12 |