1,1,3,3-Tetramethyl-disiloxane → 1-(4-Methyl-1-pentenyl)piperidine

HRID 1912040

反応式

HRID 1912040 の反応式
[CH3:1][CH:2]([CH3:13])[CH2:3][CH2:4][C:5]([N:7]1[CH2:12][CH2:11][CH2:10][CH2:9][CH2:8]1)=O.C[SiH](C)O[SiH](C)C>C1(C)C=CC=CC=1>[CH3:1][CH:2]([CH3:13])[CH2:3][CH:4]=[CH:5][N:7]1[CH2:12][CH2:11][CH2:10][CH2:9][CH2:8]1

参加物

4

反応物 2

HCID 186591,1,3,3-Tetramethyl-disiloxaneHCID 229808734-Methyl-1-(piperidin-1-YL)pentan-1-one

生成物 1

HCID 866750301-(4-Methyl-1-pentenyl)piperidine収率 248.3%

試薬・触媒・溶媒 1

HCID 1140Toluene溶媒

実験手順

4-Methyl-1-piperidin-1-ylpentan-1-one (372.4 g) and toluene (1000 mL) were mixed. To the mixture was added (Ph3P)IrCl(CO) (633 mg). In a water-bath, 1,1,3,3-tetramethyldisiloxane (627 mL) was added dropwise to the mixture. The resulting mixture was stirred at RT for 2 hr. The reaction mixture was concentrated in vacuo to give the title compound (844 g) as a crude product.

後処理

  1. concentrationThe reaction mixture was concentrated in vacuo

出典と根拠

ORDレコード
ord-356f1af117b84067a3e5097a7db678d9
出典データセット
uspto-grants-2013_12
特許番号
US08604069B2

関連ノート

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