Water → Strontium

The compounds (active strontium test-article: Sr-malonate, 189.6 g/mol; Placebo substance, calcium malonate, 142.1 g/mol) was suspended in drinking water for the rats. The salts were prepared in a solution of 1.6 g/l, which is close to saturation (22-25° C.). Thus extensive stirring was required to completely dissolve the substances. A new batch of drinking water was prepared fresh every week for the duration of the experiment. When not in use the solution was stored at room temperature in a closed container. Preliminary experiments showed that the animals each drink between 60 and 90 ml/24 h resulting in approximate strontium dosing of 120 mg strontium malonate/day equal to 55.4 mg of ionic strontium.

1. customThe salts were prepared in a solution of 1.6 g/l, which
2. customis close to saturation (22-25° C.)
3. dissolutionto completely dissolve the substances
4. customwas stored at room temperature in a closed container
5. customeach drink between 60 and 90 ml/24 h

ORDレコード

ord-7813d2de6dda428a81368bac0ce06d6b

出典データセット

uspto-grants-2013_12

DOI

10.6084/m9.figshare.5104873.v1

特許番号

US08609616B2