Methanol → HCID 10801230、化合物
反応式
[Br:1][C:2]1[CH:7]=[C:6]([O:8][CH3:9])[CH:5]=[CH:4][C:3]=1[CH2:10][C:11]([OH:13])=[O:12].[CH3:14]O>OS(O)(=O)=O>[CH3:14][O:12][C:11](=[O:13])[CH2:10][C:3]1[CH:4]=[CH:5][C:6]([O:8][CH3:9])=[CH:7][C:2]=1[Br:1]参加物
4
実験手順
To a solution of (2-bromo-4-methoxy-phenyl)-acetic acid (1.07 g, 4.37 mmol) in 25 mL MeOH was added two drops of concentrated H2SO4 and the reaction was heated to reflux. After 18 hours, the solvent was removed in vacuo to give 920 mg of (2-bromo-4-methoxy-phenyl)-acetic acid methyl ester. This material was used directly in the next step without further purification.
後処理
- temperaturethe reaction was heated to reflux
- customthe solvent was removed in vacuo
出典と根拠
- ORDレコード
- ord-08ca7c0ee84442aabfdc67bb4bf2f14c
- 出典データセット
- uspto-grants-2013_12
- 特許番号
- US08609680B2
反応ノート
読み込み中…