Sulfuryl chloride → [(Chlorocarbonyl)oxy]methyl 2-methylpropanoate
反応式
[CH3:1][CH:2]([CH3:13])[C:3]([O:5][CH2:6][O:7][C:8](SCC)=[O:9])=[O:4].S(Cl)([Cl:17])(=O)=O>>[CH3:1][CH:2]([CH3:13])[C:3]([O:5][CH2:6][O:7][C:8]([Cl:17])=[O:9])=[O:4]参加物
3
実験手順
The compound (400 mg) obtained in Step 2 of this Example was cooled to −30° C. Sulfuryl chloride (159 μL) was added thereto, and the mixture was stirred at the same temperature for 20 minutes. The mixture was in turn stirred for 20 minutes in an ice bath and further at room temperature for 1 hour. The solvent was distilled off under reduced pressure, and the residue was dried to obtain a crude product of the title compound.
後処理
- customwas cooled to −30° C
- stirringstirred for 20 minutes in an ice bath and further at room temperature for 1 hour
- distillationThe solvent was distilled off under reduced pressure
- customthe residue was dried
出典と根拠
- ORDレコード
- ord-c58152f509424c4793a0f1ef193ef4f6
- 出典データセット
- uspto-grants-2013_12
- 特許番号
- US08609710B2
反応ノート
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