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Thionyl Chloride → 3-(Chloromethyl)-9h-pyrido[3,4-b]indole
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Thionyl Chloride | HCID 24386 | — |
| 反応物 | 3-Hydroxymethyl-beta-carboline | HCID 5353338 | — |
| 生成物 | 3-(Chloromethyl)-9h-pyrido[3,4-b]indole | HCID 20148409 | — |
反応手順
The 3-(hydroxymethyl)-β-carboline was added to an excess (3 grams) of thionyl chloride and the mixture was refluxed for 1 hour. The excess thionyl chloride was then evaporated and the obtained residue was crystallized from hexane. 2.5 grams of 3-(chloromethyl)-β-carboline was obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08614319B2 |
| 出典データセット | uspto-grants-2013_12 |
| ORD ID | ord-8d8756721e9a4063a0fb838495571a2c |
| 出典メモ | uspto-grants-2013_12 |