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4-Oxo-4,5,6,7-tetrahydrobenzofuran-2-carboxylic acid → 4-Oxo-4,5,6,7-tetrahydro-benzofuran-2-carboxylic acid [2-methyl-4-(2-methyl-[1,3']bipyrrolidinyl-1'-yl)-phenyl]-amide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Oxo-4,5,6,7-tetrahydrobenzofuran-2-carboxylic acid | HCID 3471008 | — |
| 反応物 | 2-Methyl-4-(2-methyl-[1,3']bipyrrolidinyl-1'-yl)-phenylamine | HCID 59401830 | — |
| 生成物 | 4-Oxo-4,5,6,7-tetrahydro-benzofuran-2-carboxylic acid [2-methyl-4-(2-methyl-[1,3']bipyrrolidinyl-1'-yl)-phenyl]-amide | HCID 67401881 | — |
反応手順
The title compound was prepared in a manner substantially the same as example 1 by coupling 2-methyl-4-(2-methyl-[1,3′]bipyrrolidinyl-1′-yl)-phenylamine with 4-oxo-4,5,6,7-tetrahydro-benzofuran-2-carboxylic acid. MS: 422.4 (M+H).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08618159B2 |
| 出典データセット | uspto-grants-2013_12 |
| ORD ID | ord-5bb73138eecf442ca922625f7d511d39 |
| 出典メモ | uspto-grants-2013_12 |