6-Fluoro-2-methylquinoline-3-carboxylic acid → HCID 59401899、化合物

HRID 1916942ノート

反応式

HRID 1916942 の反応式
[CH3:1][C:2]1[CH:7]=[C:6]([N:8]2[CH2:12][CH2:11][CH:10]([N:13]3[CH2:17][CH2:16][CH2:15][CH:14]3[CH3:18])[CH2:9]2)[CH:5]=[CH:4][C:3]=1[NH2:19].[F:20][C:21]1[CH:22]=[C:23]2[C:28](=[CH:29][CH:30]=1)[N:27]=[C:26]([CH3:31])[C:25]([C:32](O)=[O:33])=[CH:24]2>>[CH3:1][C:2]1[CH:7]=[C:6]([N:8]2[CH2:12][CH2:11][CH:10]([N:13]3[CH2:17][CH2:16][CH2:15][CH:14]3[CH3:18])[CH2:9]2)[CH:5]=[CH:4][C:3]=1[NH:19][C:32]([C:25]1[C:26]([CH3:31])=[N:27][C:28]2[C:23]([CH:24]=1)=[CH:22][C:21]([F:20])=[CH:30][CH:29]=2)=[O:33]

参加物

3

反応物 2

HCID 6931086-Fluoro-2-methylquinoline-3-carboxylic acidHCID 594018302-Methyl-4-(2-methyl-[1,3']bipyrrolidinyl-1'-yl)-phenylamine

生成物 1

HCID 59401899HCID 59401899、化合物

実験手順

The title compound was prepared in a manner substantially the same as example 1 by coupling 2-methyl-4-(2-methyl-[1,3′]bipyrrolidinyl-1′-yl)-phenylamine with 6-fluoro-2-methyl-quinoline-3-carboxylic acid. MS: 447.4 (M+H).

出典と根拠

ORDレコード
ord-25d483f47dab43c5996d643b8edac7ab
出典データセット
uspto-grants-2013_12
特許番号
US08618159B2

反応ノート

読み込み中…