Acetic Anhydride → HCID 20544504、化合物

HRID 1919575ノート

反応式

HRID 1919575 の反応式
[NH2:1][C:2]1[S:3][C:4]([C:7]#[N:8])=[CH:5][N:6]=1.[C:9](OC(=O)C)(=[O:11])[CH3:10]>C(O)(=O)C>[C:9]([NH:1][C:2]1[S:3][C:4]([C:7]#[N:8])=[CH:5][N:6]=1)(=[O:11])[CH3:10]

参加物

4

反応物 2

HCID 7918Acetic AnhydrideHCID 100575072-Aminothiazole-5-carbonitrile

生成物 1

HCID 20544504HCID 20544504、化合物収率 80%

試薬・触媒・溶媒 1

HCID 176Acetic Acid溶媒

実験手順

2.14 g 2-Amino-5-cyanothiazole was dissolved in 10 ml acetic acid, and 1.8 ml acetic anhydride was added to carry out reaction at 100° C. for 30 min. The reaction product was cooled down, and filtered to obtain 2.5 g of a clay-solid having metallic luster (yield 80%), 1H NMR (DMSO-d6) 2.22 (3H, s), 8.36 (1H, s), 12.95 (1H, s).

後処理

  1. customreaction at 100° C. for 30 min
  2. temperatureThe reaction product was cooled down
  3. filtrationfiltered

出典と根拠

ORDレコード
ord-47e75d2f864c491e925dee59704ce60e
出典データセット
uspto-grants-2012_05
特許番号
US08168642B2

反応ノート

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