4-[1,1,1,3,3,3-hexafluoro-2-(methoxymethyl)oxypropan-2-yl]-2-[(1Z)-1-propenyl]-6-propylphenol → HCID 59234895、化合物
反応式
[F:1][C:2]([F:26])([F:25])[C:3]([C:12]1[CH:17]=[C:16]([CH2:18][CH2:19][CH3:20])[C:15]([OH:21])=[C:14](/[CH:22]=[CH:23]\[CH3:24])[CH:13]=1)([O:8][CH2:9][O:10][CH3:11])[C:4]([F:7])([F:6])[F:5]>[C].[Pd].CO>[CH2:18]([C:16]1[CH:17]=[C:12]([C:3]([O:8][CH2:9][O:10][CH3:11])([C:2]([F:1])([F:25])[F:26])[C:4]([F:5])([F:6])[F:7])[CH:13]=[C:14]([CH2:22][CH2:23][CH3:24])[C:15]=1[OH:21])[CH2:19][CH3:20]参加物
4
実験手順
Methanol (30 mL) was added to 4-[1,1,1,3,3,3-hexafluoro-2-(methoxymethyl)oxypropan-2-yl]-2-[(1Z)-1-propenyl]-6-propylphenol (1.29 g, 3.34 mmol). A 10% palladium-carbon catalyst (130 mg) was added to the mixed solution, followed by hydrogenation for 20 hours. The catalyst was separated from the reaction solution by filtration, followed by concentration under reduced pressure to obtain 929 mg of 2,6-dipropyl-4-[1,1,1,3,3,3-hexafluoro-2-(methoxymethyl)oxypropan-2-yl]phenol (yield: 72%) as white crystals.