Acetone → 4-(6-fluoro-1-methyl-1H-indazol-3-yl)-1-(3-hydroxypropyl)piperidine

反応式

[Br:24][CH2:25][CH2:26][CH2:27][OH:28].[C:18](=[O:19])([O-:20])[O-:21].[CH3:29][C:30](=[O:31])[CH3:32].[F:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([CH:12]3[CH2:13][CH2:14][NH:15][CH2:16][CH2:17]3)[n:7][n:8]([CH3:11])[c:9]2[cH:10]1.[K+:22].[K+:23]>>[F:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([CH:12]3[CH2:13][CH2:14][N:15]([CH2:25][CH2:26][CH2:27][OH:28])[CH2:16][CH2:17]3)[n:7][n:8]([CH3:11])[c:9]2[cH:10]1