Phenylhydrazine → 1-(3-Methanesulfonyl-phenyl)-3-(2-phenyl-2H-pyrazol-3-yl)-1H-pyridazin-4-one

HRID 1924508

反応式

HRID 1924508 の反応式
C[N:2](C)/[CH:3]=[CH:4]/[C:5]([C:7]1[C:12](=[O:13])[CH:11]=[CH:10][N:9]([C:14]2[CH:19]=[CH:18][CH:17]=[C:16]([S:20]([CH3:23])(=[O:22])=[O:21])[CH:15]=2)[N:8]=1)=O.[C:25]1([NH:31]N)[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1>>[CH3:23][S:20]([C:16]1[CH:15]=[C:14]([N:9]2[CH:10]=[CH:11][C:12](=[O:13])[C:7]([C:5]3[N:31]([C:25]4[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=4)[N:2]=[CH:3][CH:4]=3)=[N:8]2)[CH:19]=[CH:18][CH:17]=1)(=[O:22])=[O:21]

参加物

3

反応物 2

HCID 7516PhenylhydrazineHCID 593701713-((E)-3-Dimethylamino-acryloyl)-1-(3-methansulfonyl-phenyl)-1H-pyridazin-4-one

生成物 1

HCID 462196961-(3-Methanesulfonyl-phenyl)-3-(2-phenyl-2H-pyrazol-3-yl)-1H-pyridazin-4-one収率 47%

実験手順

The product was obtained starting from 3-((E)-3-Dimethylamino-acryloyl)-1-(3-methansulfonyl-phenyl)-1H-pyridazin-4-one (A-7) and phenylhydrazine according to the method described for Example 1 in 47% yield. MS: M=393.0 (M+H)+

後処理

  1. customThe product was obtained

出典と根拠

ORDレコード
ord-687a526e684e41a397b3c162a3bf5d8a
出典データセット
uspto-grants-2012_05
特許番号
US08178538B2

関連ノート

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