5-Hydrazinylquinoline → 3-(2-Quinolin-5-yl-2H-pyrazol-3-yl)-1-(3-trifluoromethoxy-phenyl)-1H-pyridazin-4-one
反応式
C[N:2](C)/[CH:3]=[CH:4]/[C:5]([C:7]1[C:12](=[O:13])[CH:11]=[CH:10][N:9]([C:14]2[CH:19]=[CH:18][CH:17]=[C:16]([O:20][C:21]([F:24])([F:23])[F:22])[CH:15]=2)[N:8]=1)=O.[N:26]1[C:35]2[C:30](=[C:31]([NH:36]N)[CH:32]=[CH:33][CH:34]=2)[CH:29]=[CH:28][CH:27]=1>>[N:26]1[C:35]2[C:30](=[C:31]([N:36]3[C:5]([C:7]4[C:12](=[O:13])[CH:11]=[CH:10][N:9]([C:14]5[CH:19]=[CH:18][CH:17]=[C:16]([O:20][C:21]([F:24])([F:23])[F:22])[CH:15]=5)[N:8]=4)=[CH:4][CH:3]=[N:2]3)[CH:32]=[CH:33][CH:34]=2)[CH:29]=[CH:28][CH:27]=1参加物
3
実験手順
The product was obtained starting from 3-((E)-3-Dimethylamino-acryloyl)-1-(3-trifluoromethoxy-phenyl)-1H-pyridazin-4-one (A-6) and quinolin-5-yl-hydrazine according to the method described for example 91. MS: M=450.1 (M+H)+
後処理
- customThe product was obtained