7-Chloro-4-hydrazinylquinoline → 3-[2-(7-Chloro-quinolin-4-yl)-2H-pyrazol-3-yl]-1-(4-trifluoromethoxy-phenyl)-1H-pyridazin-4-one
反応式
CN(C)/[CH:3]=[CH:4]/[C:5]([C:7]1[C:12](=[O:13])[CH:11]=[CH:10][N:9]([C:14]2[CH:19]=[CH:18][C:17]([O:20][C:21]([F:24])([F:23])[F:22])=[CH:16][CH:15]=2)[N:8]=1)=O.[Cl:26][C:27]1[CH:36]=[C:35]2[C:30]([C:31]([NH:37][NH2:38])=[CH:32][CH:33]=[N:34]2)=[CH:29][CH:28]=1>>[Cl:26][C:27]1[CH:36]=[C:35]2[C:30]([C:31]([N:37]3[C:5]([C:7]4[C:12](=[O:13])[CH:11]=[CH:10][N:9]([C:14]5[CH:15]=[CH:16][C:17]([O:20][C:21]([F:22])([F:23])[F:24])=[CH:18][CH:19]=5)[N:8]=4)=[CH:4][CH:3]=[N:38]3)=[CH:32][CH:33]=[N:34]2)=[CH:29][CH:28]=1参加物
3
実験手順
The product was obtained starting from 3-((E)-3-Dimethylamino-acryloyl)-1-(4-trifluoromethoxy-phenyl)-1H-pyridazin-4-one (A-8) and (7-chloro-quinolin-4-yl)-hydrazine according to the method described for example 91. MS: M=484.1 (M+H)+
後処理
- customThe product was obtained