5-Hydrazinylquinoline → 1-[3-(Piperidine-1-sulfonyl)-phenyl]-3-(2-quinolin-5-yl-2H-pyrazol-3-yl)-1H-pyridazin-4-one
反応式
CN(C)/[CH:3]=[CH:4]/[C:5]([C:7]1[C:12](=[O:13])[CH:11]=[CH:10][N:9]([C:14]2[CH:19]=[CH:18][CH:17]=[C:16]([S:20]([N:23]3[CH2:28][CH2:27][CH2:26][CH2:25][CH2:24]3)(=[O:22])=[O:21])[CH:15]=2)[N:8]=1)=O.[N:30]1[C:39]2[C:34](=[C:35]([NH:40][NH2:41])[CH:36]=[CH:37][CH:38]=2)[CH:33]=[CH:32][CH:31]=1>>[N:23]1([S:20]([C:16]2[CH:15]=[C:14]([N:9]3[CH:10]=[CH:11][C:12](=[O:13])[C:7]([C:5]4[N:40]([C:35]5[CH:36]=[CH:37][CH:38]=[C:39]6[C:34]=5[CH:33]=[CH:32][CH:31]=[N:30]6)[N:41]=[CH:3][CH:4]=4)=[N:8]3)[CH:19]=[CH:18][CH:17]=2)(=[O:22])=[O:21])[CH2:28][CH2:27][CH2:26][CH2:25][CH2:24]1参加物
3
実験手順
The product was obtained starting from 3-((E)-3-Dimethylamino-acryloyl)-1-[3-(piperidine-1-sulfonyl)-phenyl]-1H-pyridazin-4-one (A-26) and quinolin-5-yl-hydrazine according to the method described for example 91. MS: M=513.4 (M+H)+
後処理
- customThe product was obtained