Hydrochloric Acid → HCID 135995200、化合物
反応式
[CH3:1][C:2]1[N:3]=[C:4]([C:8]2[C:9]([O:16]C)=[N:10][C:11]([O:14]C)=[N:12][CH:13]=2)[S:5][C:6]=1[CH3:7].Cl>O1CCOCC1>[CH3:1][C:2]1[N:3]=[C:4]([C:8]2[C:9](=[O:16])[NH:10][C:11](=[O:14])[NH:12][CH:13]=2)[S:5][C:6]=1[CH3:7]参加物
4
実験手順
(5-(4,5-dimethyl-1,3-thiazol-2-yl)-2,4-bis(methyloxy)pyrimidine) (Prep14, 118 mg, 0.470 mmol) in HCl (5.87 ml, 23.48 mmol) 4M in dioxane was stirred in a closed tube at 90° C. for 1.5 hour. Then the mixture was cooled to rt and the solvent evaporated under vacuum to afford the title compound as a pale grey solid (153 mg)
後処理
- customthe solvent evaporated under vacuum
出典と根拠
- ORDレコード
- ord-5d8f4f088ea94406982bd822478c6c80
- 出典データセット
- uspto-grants-2012_05
- 特許番号
- US08178549B2
反応ノート
読み込み中…