Ethylamine → L-Theanine
反応式
CO[C:3]([CH2:5][CH2:6][C@H:7]([NH2:11])[C:8]([OH:10])=[O:9])=[O:4].C(CC(=O)C)(=O)C.[C:19]([NH2:23])(C)(C)[CH3:20].C(N)C>CO>[NH2:11][C@H:7]([C:8]([OH:10])=[O:9])[CH2:6][CH2:5][C:3]([NH:23][CH2:19][CH3:20])=[O:4]参加物
6
反応条件
- 温度
- 60 °C
実験手順
First, 5.0 g (31 mmol) of L-glutamic acid-γ-methyl ester was suspended in 15 mL of methanol. To this, 3.4 g (34 mmol) of acetylacetone and 2.3 g (31 mmol) of t-butylamine were added. The mixture was heated at 60° C. for 2 hours. Subsequently, 20 g (310 mmol) of 70% ethylamine was added to the mixture and the same procedure as in Example 1 was performed to obtain 3.6 g of theanine (yield: 66.7%). The obtained theanine had the same purity as high as in Example 1.
出典と根拠
- ORDレコード
- ord-185e19505cb543bf9d781bbd31429b38
- 出典データセット
- uspto-grants-2012_05
- 特許番号
- US08178722B2
反応ノート
読み込み中…