反応式
CO[C:3]([CH2:5][CH2:6][C@H:7]([NH2:11])[C:8]([OH:10])=[O:9])=[O:4].C(C1CCCC1=O)(=O)C.[CH2:21]([N:23](CC)CC)[CH3:22].C(N)C>CO>[NH2:11][C@H:7]([C:8]([OH:10])=[O:9])[CH2:6][CH2:5][C:3]([NH:23][CH2:21][CH3:22])=[O:4]参加物
6
反応条件
- 温度
- 60 °C
実験手順
First, 5.0 g (31 mmol) of L-glutamic acid-γ-methyl ester was suspended in 15 mL of methanol. To this, 4.3 g (34 mmol) of 2-acetyl-cyclopentanone and 3.1 g (31 mmol) of triethylamine were added. The mixture was heated at 60° C. for 2 hours. Subsequently, 20 g (310 mmol) of 70% ethylamine was added to the mixture and the same procedure as in Example 1 was performed to obtain 3.6 g of theanine (yield: 66.7%). The obtained theanine had the same purity as high as in Example 1.
出典と根拠
- ORDレコード
- ord-578b4314d3964a6ab643672c3e142ed7
- 出典データセット
- uspto-grants-2012_05
- 特許番号
- US08178722B2
関連ノート
読み込み中…