3-Amino-2-fluorobenzotrifluoride → 2-Chloro-7-(trifluoromethyl)benzo[d]thiazole
反応式
F[C:2]1[C:8]([C:9]([F:12])([F:11])[F:10])=[CH:7][CH:6]=[CH:5][C:3]=1[NH2:4].SC1SC2C(C(F)(F)F)=CC=CC=2N=1.[Cl:27][C:28]1[S:29]C2C=CC(Cl)=CC=2N=1>>[Cl:27][C:28]1[S:29][C:2]2[C:8]([C:9]([F:12])([F:11])[F:10])=[CH:7][CH:6]=[CH:5][C:3]=2[N:4]=1参加物
4
反応条件
- 温度
- 90 °C
実験手順
The title compound was prepared from 2-fluoro-3-trifluoromethylaniline via 2-mercapto-7-trifluoromethyl-1,3-benzothiazole as described for 2,5-dichloro-1,3-benzothiazole except that in the first step the reaction mixture was heated to 90° C. for 4 h.
出典と根拠
- ORDレコード
- ord-20c89ecd561b48d1917be10f90a8064d
- 出典データセット
- uspto-grants-2012_05
- 特許番号
- US08178668B2
反応ノート
読み込み中…