HCID 57468723、化合物 → HCID 24760433、化合物
反応式
[NH2:1][C:2]1[CH:11]=[CH:10][C:5]([C:6]([NH:8][OH:9])=[NH:7])=[CH:4][N:3]=1.[CH3:12][C:13]1[N:18]=[C:17]([C:19](O)=O)[CH:16]=[C:15]([C:22]2[CH:27]=[CH:26][C:25]([C:28]([F:31])([F:30])[F:29])=[CH:24][CH:23]=2)[CH:14]=1>>[CH3:19][C:17]1[N:18]=[C:13]([C:12]2[O:9][N:8]=[C:6]([C:5]3[CH:10]=[CH:11][C:2]([NH2:1])=[N:3][CH:4]=3)[N:7]=2)[CH:14]=[C:15]([C:22]2[CH:23]=[CH:24][C:25]([C:28]([F:31])([F:30])[F:29])=[CH:26][CH:27]=2)[CH:16]=1参加物
3
実験手順
The title compound was prepared from 6-amino-N-hydroxy-nicotinamidine (example C.3) (0.113 g, 0.53 mmol) and 6-methyl-4-(4-trifluoromethyl-phenyl)-pyridine-2-carboxylic acid (example D.11) (0.10 g, 0.36 mmol) according to the general procedure V. Obtained as an off-white solid (0.045 g, 31%). MS (ISP) 398.1 [(M+H)+]; mp 163° C.
出典と根拠
- ORDレコード
- ord-ed56a4bd38f14cabb625fc2725357b4c
- 出典データセット
- uspto-grants-2012_05
- 特許番号
- US08183262B2
反応ノート
読み込み中…