(R)-N2-Indan-1-yl-quinoline-2,6-diamine → N-(cyclopropylmethyl)-N'-{2-[(1R)-2,3-dihydro-1H-inden-1-ylamino]quinolin-6-yl}-N-methylsulfamide
反応式
FC(F)(F)S([O-])(=O)=O.[CH:9]1([CH2:12][N:13]([CH3:23])[S:14]([N:17]2[CH:21]=[CH:20][N+](C)=C2)(=[O:16])=[O:15])[CH2:11][CH2:10]1.[C@H:24]1([NH:33][C:34]2[CH:43]=[CH:42][C:41]3[C:36](=[CH:37][CH:38]=C(N)C=3)[N:35]=2)[C:32]2[C:27](=[CH:28][CH:29]=[CH:30][CH:31]=2)[CH2:26][CH2:25]1>>[CH:9]1([CH2:12][N:13]([CH3:23])[S:14]([NH:17][C:21]2[CH:20]=[C:41]3[C:36](=[CH:37][CH:38]=2)[N:35]=[C:34]([NH:33][C@H:24]2[C:32]4[C:27](=[CH:28][CH:29]=[CH:30][CH:31]=4)[CH2:26][CH2:25]2)[CH:43]=[CH:42]3)(=[O:15])=[O:16])[CH2:10][CH2:11]1参加物
3
実験手順
The title compound was prepared in accordance with step C of the general method described in example 76 from 3-(cyclopropylmethyl-methyl-sulfamoyl)-1-methyl-3-H-imidazol-1-ium trifluoromethanesulfonate and (R)—N2-indan-1-yl-quinoline-2,6-diamine; MS: m/e=423.7 (M+H+).
出典と根拠
- ORDレコード
- ord-1f4e993be2a34aff84b8e72e7775a51c