(4-Methylpiperazin-1-yl)acetic acid → Rac-n-[2-(6-fluoro-indan-1-ylamino)-quinolin-6-yl]-2-(4-methyl-piperazin-1-yl)-acetamide
反応式
[F:1][C:2]1[CH:10]=[C:9]2[C:5]([CH2:6][CH2:7][CH:8]2[NH:11][C:12]2[CH:21]=[CH:20][C:19]3[C:14](=[CH:15][CH:16]=[C:17]([NH2:22])[CH:18]=3)[N:13]=2)=[CH:4][CH:3]=1.[CH3:23][N:24]1[CH2:29][CH2:28][N:27]([CH2:30][C:31](O)=[O:32])[CH2:26][CH2:25]1>>[F:1][C:2]1[CH:10]=[C:9]2[C:5]([CH2:6][CH2:7][CH:8]2[NH:11][C:12]2[CH:21]=[CH:20][C:19]3[C:14](=[CH:15][CH:16]=[C:17]([NH:22][C:31](=[O:32])[CH2:30][N:27]4[CH2:28][CH2:29][N:24]([CH3:23])[CH2:25][CH2:26]4)[CH:18]=3)[N:13]=2)=[CH:4][CH:3]=1参加物
3
実験手順
The title compound was prepared in accordance with the general method 14 described in example 119 from rac-N2-(6-fluoro-indan-1-yl)-quinoline-2,6-diamine and (4-methyl-piperazin-1-yl)-acetic acid; MS: m/e=434.5 (M+H+).
出典と根拠
- ORDレコード
- ord-1decd402ceb44d7ca7c10b508fc9e3fc
- 出典データセット
- uspto-grants-2012_05