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HRID 1929567作成日:2026年10月27日

Methyl 6-fluoro-4-hydroxy-2-naphthoate → 6-Fluoro-4-hydroxy-3-methyl-naphthalene-2-carboxylic acid methyl ester

https://huagongshe.com/reaction/1929567

反応式

関与物質

役割名称HCID仕込み量
反応物Methyl 6-fluoro-4-hydroxy-2-naphthoateHCID 59326505—
反応物2-(4-Fluoro-benzylidene)-3-methyl-succinic acid 1-methyl esterHCID 66775587—
生成物6-Fluoro-4-hydroxy-3-methyl-naphthalene-2-carboxylic acid methyl esterHCID 59326573—

反応手順

Alternatively, Starting with 2-(4-fluoro-benzylidene)-3-methyl-succinic acid 1-methyl ester, using a method analogous to the one described above for 6-fluoro-4-hydroxy-naphthalene-2-carboxylic acid methyl ester, 6-fluoro-4-hydroxy-3-methyl-naphthalene-2-carboxylic acid methyl ester was obtained as a pale solid.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US08188090B2
出典データセットuspto-grants-2012_05
ORD IDord-09f9221f91c1416bacfd5a53a902d297
出典メモuspto-grants-2012_05