2-(2,4-Dimethyl-1H-imidazol-1-yl)ethanamine → 8-[2-(2,3-Dimethylphenyl)ethyl]-1,3-dimethyl-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine

HRID 1929678ノート

反応式

HRID 1929678 の反応式
[CH3:1][C:2]1[N:3]([CH2:8][CH2:9][NH2:10])[CH:4]=[C:5]([CH3:7])[N:6]=1.[CH3:11][C:12]1[C:17]([CH3:18])=[CH:16][CH:15]=[CH:14][C:13]=1[CH2:19][CH2:20][CH:21]=O>>[CH3:11][C:12]1[C:17]([CH3:18])=[CH:16][CH:15]=[CH:14][C:13]=1[CH2:19][CH2:20][CH:21]1[NH:10][CH2:9][CH2:8][N:3]2[C:2]([CH3:1])=[N:6][C:5]([CH3:7])=[C:4]12

参加物

3

反応物 2

HCID 184607002-(2,4-Dimethyl-1H-imidazol-1-yl)ethanamineHCID 219896293-(2,3-Dimethylphenyl)propanal

生成物 1

HCID 667339628-[2-(2,3-Dimethylphenyl)ethyl]-1,3-dimethyl-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine

実験手順

Prepared according to the previously described general procedure (GP11) by reaction of 2-(2,4-dimethyl-imidazol-1-yl)-ethylamine with 3-(2,3-dimethyl-phenyl)-propionaldehyde. LC-MS: tR=0.61 min.; [M+H]+=284 g/mol.

後処理

  1. customPrepared

出典と根拠

ORDレコード
ord-179dff81f2434ed6a298d00c0f7b5ddb
出典データセット
uspto-grants-2012_05
特許番号
US08188082B2

反応ノート

読み込み中…