Tert-butyl propionylcarbamate → [(1S,4R)-4-(2,6-Dichloro-purin-9-yl)-cyclopent-2-enyl]-propionyl-carbamic acid tert-butyl ester

HRID 1929769ノート

反応式

HRID 1929769 の反応式
[C:1]([N:8]([C:25]([O:27]C(C)(C)C)=O)[C@H:9]1[CH2:13][C@@H:12]([N:14]2[CH:22]=[N:21][C:20]3[C:15]2=[N:16][C:17]([Cl:24])=[N:18][C:19]=3[Cl:23])[CH:11]=[CH:10]1)([O:3][C:4]([CH3:7])([CH3:6])[CH3:5])=[O:2].[C:32](OC(=O)NC(=O)CC)(C)(C)[CH3:33]>>[C:4]([O:3][C:1](=[O:2])[N:8]([C@H:9]1[CH2:13][C@@H:12]([N:14]2[CH:22]=[N:21][C:20]3[C:15]2=[N:16][C:17]([Cl:24])=[N:18][C:19]=3[Cl:23])[CH:11]=[CH:10]1)[C:25](=[O:27])[CH2:32][CH3:33])([CH3:5])([CH3:7])[CH3:6]

参加物

3

反応物 2

HCID 14221819Tert-butyl propionylcarbamateHCID 58025018Di-Boc-[(1S,4R)-4-(2,6-dichloro-purin-9-yl)-cyclopent-2-enyl]-amine

生成物 1

HCID 86622633[(1S,4R)-4-(2,6-Dichloro-purin-9-yl)-cyclopent-2-enyl]-propionyl-carbamic acid tert-butyl ester

実験手順

The title compound is prepared analogously to di-Boc-[(1S,4R)-4-(2,6-dichloro-purin-9-yl)-cyclopent-2-enyl]-amine (by replacing di-t-butyliminodicarboxylate with propionyl-carbamic acid tert-butyl ester.

出典と根拠

ORDレコード
ord-f09b24bc4b864f949154268a1133b715
出典データセット
uspto-grants-2012_05
特許番号
US08188100B2

反応ノート

読み込み中…