Dimethylformamide dimethyl acetal → Ethenamine, N,N-dimethyl-2-[2-nitro-6-(trifluoromethyl)phenyl]-, (1E)-
反応式
[CH3:1][C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][CH:5]=[CH:4][C:3]=1[C:11]([F:14])([F:13])[F:12].CO[CH:17](OC)[N:18]([CH3:20])[CH3:19]>CN(C)C=O>[CH3:17][N:18]([CH3:20])/[CH:19]=[CH:1]/[C:2]1[C:3]([C:11]([F:12])([F:13])[F:14])=[CH:4][CH:5]=[CH:6][C:7]=1[N+:8]([O-:10])=[O:9]参加物
4
実験手順
A solution of 17 mmol 2-methyl-3-nitrobenzotrifluoride and 43 mmol N,N-dimethylformamide-dimethylacetal in 30 ml N,N-dimethylformamide was hold at 120° C. overnight. The reaction mixture is concentrated in vacuo to give the crude title compound. Yield 83%. MS (m/e): 261.1 ([M+H]+, 90%).
後処理
- customat 120° C.
- customovernight
- concentrationThe reaction mixture is concentrated in vacuo
出典と根拠
- ORDレコード
- ord-f6b7286e789142dca26862f2591604a1
- 出典データセット
- uspto-grants-2012_05
- 特許番号
- US08188139B2
反応ノート
読み込み中…