化工社化工社 化学情報印刷レポート · 研究参考用
Thionyl Chloride → 3-(4-Methoxyphenyl)-2-phenylpropionyl chloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Thionyl Chloride | HCID 24386 | — |
| 反応物 | 3-(4-Methoxyphenyl)-2-phenylpropionic acid | HCID 97739 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | 3-(4-Methoxyphenyl)-2-phenylpropionyl chloride | HCID 11140323 | — |
反応手順
3-(4-Methoxyphenyl)-2-phenylpropanoic acid (12.5 g, 0.049 mol) was converted to its acid chloride by treatment with thionyl chloride (8.2 ml) in dry dichloromethane (75 ml) at 40° C. Excess thionyl chloride and dichloromethane were evaporated off. The crude product was used in the next step without purification.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06388090B2 |
| 出典データセット | uspto-grants-2002_05 |
| ORD ID | ord-8330fac80b4f466ab997698fb37b3886 |
| 出典メモ | uspto-grants-2002_05 |