5-Amino-1-(2-fluorobenzyl)-1H-indazole → (1-(2-Fluorobenzyl)-1H-indazol-5-yl)-(6-(5-methyl-1,3,4-oxadiazol-2-yl)-quinazolin-4-yl)-amine hydrochloride
反応式
[F:1][C:2]1[CH:18]=[CH:17][CH:16]=[CH:15][C:3]=1[CH2:4][N:5]1[C:13]2[C:8](=[CH:9][C:10]([NH2:14])=[CH:11][CH:12]=2)[CH:7]=[N:6]1.[Cl:19][C:20]1[C:29]2[C:24](=[CH:25][CH:26]=[C:27]([C:30]3[O:31][C:32]([CH3:35])=[N:33][N:34]=3)[CH:28]=2)[N:23]=[CH:22][N:21]=1>>[ClH:19].[F:1][C:2]1[CH:18]=[CH:17][CH:16]=[CH:15][C:3]=1[CH2:4][N:5]1[C:13]2[C:8](=[CH:9][C:10]([NH:14][C:20]3[C:29]4[C:24](=[CH:25][CH:26]=[C:27]([C:30]5[O:31][C:32]([CH3:35])=[N:33][N:34]=5)[CH:28]=4)[N:23]=[CH:22][N:21]=3)=[CH:11][CH:12]=2)[CH:7]=[N:6]1参加物
3
実験手順
The title compound was prepared according to Procedure A from 1-(2-fluorobenzyl)-1H-indazol-5-ylamine and 4-chloro-6-(5-methyl-1,3,4-oxadiazol-2-yl)-quinazoline; δH [2H6]DMSO 11.70(1H,s), 9.45(1H,s), 8.90(1H,s), 8.60(1H,d), 8.20(1H,s), 8.13(1H,s), 7.85(1H,d), 7.70(1H,d), 7.38(1H,m), 7.24 (1H,m), 7.17 (3H,m), 5.76(2H,s), 2.65 (3H,s); m/z (M+1+) 452.
出典と根拠
- ORDレコード
- ord-cb97df37ffd64cbabc895dc2536ffd21
- 出典データセット